Monasterium Laboratory has access to the human skin re-innervation model developed by the Misery Lab, University of Brest, where full-thickness skin is co-cultured with and re-innervatived by primary rat dorsal root ganglion neurons. Moreover, we have developed a fully humanized skin re-innervation assay using human neuronal progenitor cells (derived from human induced pluripotent stem cells).
With these models, the vitality of skin samples cultured ex vivo in serum-free medium can be substantially prolonged and test agents added to the medium (mimicking systemic delivery) or directly onto the epidermis at the air-liquid interphase (testing topical agent application).
For service / collaboration inquiries, please contact:
Principle Scientist: Dr. Marta Bertolini
phone: +49 (0)251 93264-456
Chief Executive Officer: Anja Borrosch
phone: +49 (0)251 93264-458
Chief Consultant: Prof. Dr. Ralf Paus